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2008-09-05T04:13:12Z
SodaHead Users
4 simple rules to live by for a happier life.....
http://sodahead.com/blog/13984
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<small>Pheno</small></a>
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1. Be Impeccable With Your Word
Speak with integrity. Say only what you mean. Avoid using the word to
speak against yourself or to gossip about others. Use the power of your
word in the direction of truth and love.
2. Don't Take Anything Personally
Nothing others do is because of you. What others say and do is a
projection of their own reality, their own dream. When you are immune tothe opinions and actions of others, you won't be the victim of needless suffering.
3. Don't Make Assumptions
Find the courage to ask questions and to express what you really want.
Communicate with others as clearly as you can to avoid misunderstandings,sadness and drama. With just this one agreement, you can completely transform your life.
4. Always Do Your Best
Your best is going to change from moment to moment; it will be different when you are healthy as opposed to sick. Under any circumstance, simply do your best, and you will avoid self-judgment, self-abuse and regret
2008-09-05T04:13:12Z
Pheno
Cholesterol Drug Scare Shenanigans (www.junkscience.com)
http://sodahead.com/blog/13939
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<small>art.and.apples</small></a>
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Cholesterol Drug Scare Shenanigans
By Steven Milloy
September 4, 2008
Why is the editor of the New England Journal of Medicine encouraging a cancer scare over the cholesterol-lowering drug Vytorin? Is he overcompensating for past bad behavior?
Prescribed for millions of patients, Vytorin is a single pill combining the cholesterol-lowering medicines Zocor and Zetia. Its popularity declined in early 2008 after several studies questioned whether Vytorin produced any health benefit and a panel of cardiologists recommended that the drug be used only as a last resort.
Then, in July, a Norwegian researcher reported that, in a clinical trial known as SEAS, 102 patients taking Vytorin developed cancer compared with 67 patients taking a placebo -- a statistically significant result indicating that chance could be ruled out with some degree of confidence as the cause.
Drug companies Merck and Schering-Plough, the makers of Zocor and Zetia, respectively, subsequently commissioned famed epidemiologist Richard Peto of Oxford University to evaluate the SEAS results. Those findings were published this week on the web site of the New England Journal of Medicine.
Based on his review of SEAS and two other ongoing Vytorin trials (called SHARP and IMPROVE-IT), Peto concluded that the trials provided no credible link between Vytorin and cancer risk, although follow-up would be needed to make a more reliable determination.
Peto based his conclusion on the fact that in the SEAS trial, there were no statistically significant increases in any specific type of cancer the statistically significant result occurred only by adding all cancers together. Moreover, for the three specific cancers with reported risks closest to attaining statistical significance in the SEAS trial -- skin, stomach and prostate -- the results were precisely the opposite of what occurred in the SHARP and IMPROVE-IT trials. That is, in those trials, placebo patients had higher rates of cancer at those sites than did Vytorin users.
Additionally, Peto found no increase in risk of cancer over time in the three trials -- generally, cancer risk increases with increasing exposure to a cancer-causing substance. This observation, he acknowledged, will also require more follow-up since the patients in the trials have only been followed for a few years.
Although more Vytorin users than placebo patients died from cancer in all three trials, the result was only statistically significant in the SEAS trial. But Peto dismissed the SEAS result since it was what had generated all the controversy in the first place and so couldn’t be used to verify the validity of a link between Vytorin and cancer. More telling than overall cancer deaths, however, was the lack of a statistically significant excess number of deaths from any specific type of cancer.
Though the available data don’t absolutely prove that Vytorin doesn’t increase cancer risk, there seems to be no good reason to think that it does -- unless you’re the editor of the New England Journal of Medicine.
In an editorial accompanying the Peto analysis, editor Jeffrey Drazen wrote that, “Although the Oxford group may ultimately prove to be correct, it is appropriate to raise a note of caution.” Without providing any back-up scientific data, Drazen then speculated that since Vytorin works by interfering with the gastrointestinal absorption of cholesterol, it might also interfere with the absorption of other unnamed molecular entities that “could conceivably affect the growth of cancer cells.” Drazen also was unwilling to cede that higher cancer death rate of Zetia patients was simply due to chance “until further data are in.”
But the main reason that Drazen is simply wrong about keeping the Vytorin cancer scare on life support is that there’s no evidence whatsoever that the drug is associated with any specific form of cancer at any specific site.
For example, excessive smoking is associated with lung cancer and occupational asbestos exposure is associated with mesothelioma. But given a specific route of exposure, no potential carcinogen is known to cause cancer at multiple sites on a random or haphazard basis. Aggregating different cancers into a catch-all “all cancer” category simply lacks demonstrable biological plausibility.
Drazen’s insistence on waiting for more data on cancer deaths is similarly nonsensical. Vytorin would first need to be associated with an increased risk of a death from a specific form of cancer -- a notion clearly contradicted by the data so far.
None of this should be controversial or new to Drazen. So what’s up with him?
Prior to becoming editor of the New England Journal of Medicine, Drazen had close ties with many drug companies -- and once got into trouble because of them.
In March 1999, the Food and Drug Administration found that Drazen made “false and misleading” statements about the safety and efficacy of the asthma drug levalbuterol made by Sepracor -- a drug company that hired Drazen to review two studies on the drug and then to comment to a company interviewer. Needless to say, given this past, his NEJM appointment was somewhat controversial.
So since becoming editor, Drazen has seemingly gone out of his way to turn on the hand that once fed him. In a May 2005 Wall Street Journal article entitled, “Medical Editor Turns Activist On Drug Trials,” former NEJM editor Marcia Angell said that, “[Drazen’s] been converted. Through painful experience, Jeff is learning what these companies are about. He sees the ugly side that he hadn’t seen before -- the bias that company-sponsored research contains, the suppression of results that they don’t like, the spin of unfavorable results.” Dr. Angell would apparently have us believe that Sepracor forced or tricked Drazen into say “false and misleading” things about their drug.
So now it seems that instead of pro-drug company bias and spin, Drazen now leans toward anti-drug company bias and spin. Imagine if Drazen were just to stick to science in the first place, he wouldn’t have worry about shifting alliances to atone for past mistakes.
Steven Milloy publishes JunkScience.com. He is a junk science expert, and advocate of free enterprise and an adjunct scholar at the Competitive Enterprise Institute.
2008-09-04T22:15:12Z
art.and.apples
this is a blog.....ohhh the irony
http://sodahead.com/blog/13910
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<small>MIss Placed</small></a>
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this day
this time
these people
i ryme
ill tell you a story
about a young girl
who llived in a hurry
and forgot the whole world
she could care less about you
could care less about me
and yes she most definatly could care less about the bum on the street
she was a blank young girl
oh such a waste
he parents often yelled at her for eating paste
she lived in such a hurry
for such a slow mind
she was not the brightest child from mankind
she was stupid and dumb
she couldnt talk let alone run
her life was a blur
but what could she do?
she was stuck in this world just like me and you
her name of course was shelly
though most people called her smelly
such a poor girl
such a waste
shell never amount to anything
she stays in the same place
if only she knew what the real world was like
shed be gald for bein the way she is
shed deal with the names
the funny way she walks
the odd was she sounds when she tryes to talk
and this is the end of our pathetic story
of a retarded girl
in a fucked up world
2008-09-04T19:31:48Z
MIss Placed
Vegetarianism
http://sodahead.com/blog/13804
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<small>Poet003</small></a>
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Vegetarianism is not proper diet in my opinon.Both men and women
need meat including red meat or they will eventually become
ANEMIC. Perhaps this symbolizes the ultimate sacrifice
Jesus the fattened calf and us the prodigal son.We should
unite our sufferings to Jesus our father , brother, husband,
and friend.He is all things to all men.
2008-09-03T23:59:23Z
Poet003
Chantix
http://sodahead.com/blog/13737
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<small>chantix</small></a>
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A perfect drug used as a smoking cessation medicine, <A href="http://www.chantix4u.com/" target="_blank" rel="nofollow">Chantix</A> is best treatment for the people who smoke. It is used together with behavior modification and counseling support to help you stop smoking cigarettes. Chantix works in the brain to block the pleasurable effects of smoking. This helps to decrease your desire to keep smoking
chantix: <A href="http://www.chantix4u.com" target="_blank" rel="nofollow">http://www.chantix4u.com</A>
2008-09-03T12:41:29Z
chantix
Obama NO WAY
http://sodahead.com/blog/13735
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<small>sdkid</small></a>
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If Obama becomes our next president I have already deceided that I will stop working. No income, no taxes, no income I can then collect food stamps, get my rent and utilities paid for, no hospital bills. What more can I ask for????
I have good friends in Canada and they said since their healthcare became nationalized thing have gotten terrible. No mater how sick you are that you can even be bleeding inside it takes 2-3 months to get to see a doctor. The people that have the money and live close to the US border will come here and without an appointment thet see a doctor in 2 hours.
Is this what you people want??
2008-09-03T12:22:48Z
sdkid
gah the pain, the pain of it all!! (some swearing)
http://sodahead.com/blog/13729
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<small>Sweetness</small></a>
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ok
so you see i had this week,
well last week actually,
where the only thing keeping me alive was caffine
and so i was having sort of 4-6 coffee's a day
only for like 5 days
but still
and so i'm guessing you all know that caffine is a drug
a very legal drug but one all the same
and so i got addicted to caffine
and this week i've had to stop drinking it all together because people have noticed i've been a bit...
paranoid...
to say the least
and so i told myself to stop
and you know what?
I HAVE WITHDRAWAL SYMTOMS AND IT FUCKING HURTS LIKE THERE IS A LITTLE MAN IN MY HEAD WITH A FUCKING CHAINSAW RIPPING MY BRAINS TO SHREADS!!!!!!!!!!!!!!!!!!!!!!!!!
and it hurts
and the paracetamol product i have doesn't work
and thats the only painkiller i have access to
and i don't wanna od on THAT
so i'm not gonna take to much
but it hurts
and i never thought caffine was capable of such a thing
and i feel betrayed by it
and i have a guitar lesson in...
half an hour
and my head hurts LIKE A MOTHERFUCKER
gah...
so yeah, just complaining to you guys about it...
and warning you
caffine is just out to get you
it'll stab you in the back when you need it the most...
O.o
2008-09-03T06:27:19Z
Sweetness
Social Vibe
http://sodahead.com/blog/13710
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<small>Miss Kellyy</small></a>
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<P><embed src="http://media.socialvibe.com/sv2.swf" allownetworking="internal" wmode="transparent" allowScriptAccess="never" enableHREF="false" height="348" width="316" enableJSURL="false" orig_size="316x348" type="application/x-shockwave-flash" flashvars="s=12-345633"/>
<A href="http://www.socialvibe.com/?r=225396&rs=join_sv" target="_blank" rel="nofollow"><img orig_size="205x17" width="205" src="http://media.socialvibe.com/m/badge/join_sv.png" border="0" height="17"/></A>
It's for a good cause and you should help me out.
2008-09-03T01:30:47Z
Miss Kellyy
Ick
http://sodahead.com/blog/13629
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<small>TwilightPrincess(Arison-san)</small></a>
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<b>+7 raves</b>
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First off, thanks to everyone who left me nice comments about my video ^___^
Secondly, having allergies sucks. It's allergy season for me, and I'm hating it. T____T
2008-09-02T02:50:36Z
TwilightPrincess(Arison-san)
i need advice...
http://sodahead.com/blog/13603
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<small>Lexi</small></a>
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I think my freinds doing drugs and iam worried about her shes getting addicted!! every half an hour shes got to go for "a walk" but everyone nos what shes doing!! :( iam worried about her not like anyone really cares iam just venting! but anyone have any suggestions.. what would you do??
Please help,
-Lexi-
2008-09-01T23:00:02Z
Lexi